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Margaret Macdonald Mackintosh (5 November 1864 – 7 January 1933), was a notable artist and designer of gesso panels and metalwork. Margaret and her sister Frances were day students at the Glasgow School of Art, and worked together until Frances’s marriage to James Herbert MacNair and Margaret's marriage Charles Rennie Mackintosh, both prominent artists. Charles Rennie Mackintosh and Margaret Macdonald collaborated on many projects. Gesso panels designed by Macdonald for the Vienna Secession Exhibition 1900 Mackintosh room were hugely popular. Macdonald and Mackintosh were feted by their hosts and have been driven through the streets of Vienna in a rose bedecked wagon.

Margaret Macdonald Mackintosh (1864-1933) was a Scottish artist and designer, who played a significant role in the Glasgow Style movement of the late 19th and early 20th century. She was born in Tipton, near Wolverhampton, England, but grew up in Scotland. Margaret Mackintosh was part of a group of artists, including her husband Charles Rennie Mackintosh, her sister Frances Macdonald, and her brother-in-law Herbert MacNair, who were all associated with the Glasgow School of Art. Together, they developed a distinctive style characterized by its use of stylized floral motifs, flowing lines, and a limited color palette. Margaret's work encompassed a wide range of media, including watercolors, metalwork, textiles, and interior design. Her most famous works are probably her watercolor paintings, which often feature ethereal figures and delicate, sinuous lines. She also produced a number of iconic textile designs, such as the "Gesso" and "Mackintosh Rose" patterns, which were used in a variety of applications, from curtains to furniture upholstery. Margaret Mackintosh's work was highly influential in the development of the Art Nouveau and Art Deco movements, and she remains a significant figure in the history of design and the decorative arts.