The Journal of nervous and mental disease (1874) (14804610063)

Identifier: journalofnervous48ameruoft (find matches)
Title: The Journal of nervous and mental disease
Year: 1874 (1870s)
Authors: American Neurological Association
Subjects: Nervous system Psychology, Pathological
Publisher: Baltimore (etc.) Williams & Wilkins (etc.)
Contributing Library: Internet Archive
Digitizing Sponsor: Internet Archive



Text Appearing Before Image:
ltration of the Virchow-Robin spaces with lymphocytes and veryfew polymorphonuclear leucocytes. This same phenomenon is mostmarked in the vessel branches which arise from the anterior spinalartery. The more posterior portion of the cord the less pronouncedis the vascular infiltration. In the gray matter, the anterior horncells are all more or less affected. No normal cells are seen and atbest one sees acute cloudy swelling of advanced grade with brokennuclei. In all of the nerve cells phagocytes are seen in varyingnumbers. From ten to twelve in the better preserved cells, to hun-dreds in those whose cell morphology shows nothing approachingthe normal. These phagocytes consist for the most part of round PATHOLOGY OF POLIOMYELITIS 231 cells with homogeneous staining cytoplasm, and are probably poly-morphonuclear leucocytes. The remaining phagocytes are roundcells each with a single irregular nucleus containing considerablechromatin and an irregular dense network. Except for the clusters
Text Appearing After Image:
Fig. 21. Section of anterior horn of monkey 1054, X 300. Acute cloudyswelling with moderate neuronophagy without chromatolysis. of polyblasts and polynuclear leucocytes here in the degeneratingcells, one sees a striking absence of all changes elsewhere in thegray matter. There are no massive clumps of polyblasts and lymphelements anywhere and the neuroglia cells are not increased innumber. 232 HUBERT S. HOWE In the posterior horns, however, one sees a rather different pic-ture. Here all changes are much less marked and although thenerve cells show some degree of acute cloudy swelling, nevertheless,what neuronophagy exists is very slight. Seldom, if ever, are more