Madonna and Child Enthroned with Saint John the Evangelist, Saint Peter, Saint Agnes, Saint Catherine of Alexandria, Saint Lucy, an Unidentified Female Saint, Saint Paul, and Saint John the Baptist, with Eve and the Serpent; the Annunciation

Public domain reproduction of artwork, 15th-16th century, free to use, no copyright restrictions image - Picryl description

The Annunciation is a biblical event in which the angel Gabriel appeared to the Virgin Mary to announce that she had been chosen to give birth to Jesus, the Son of God. The event is recorded in the New Testament in the Gospels of Luke and is a central moment in the story of the Nativity of Jesus. The scene typically depicts Mary and Gabriel, who is usually shown holding a lily, a symbol of purity, and announcing the news of the birth of Jesus to Mary.

St. Catherine of Alexandria was a 4th-century Christian martyr and saint. According to tradition, she was a learned and beautiful woman who converted to Christianity and became a noted defender of the faith. She was imprisoned and subjected to various tortures, including being broken on a wheel, but survived. She is said to have converted the emperor Maxentius to Christianity before her ultimate execution. St. Catherine is the patron saint of philosophers, students, and preachers and is venerated by the Roman Catholic, Orthodox, and Coptic Churches.

The image of Mary holding the Christ Child is a common depiction in Christian art and is known as the "Madonna and Child." It represents the mother of Jesus and her son and is a symbol of motherhood, love, and compassion.